OR14. Cardiac Index by Right Heart Catheterization was an Independent Predictor of Mortality in Adult Pulmonary Arterial Hypertension-associated with Congenital Heart Disease with Shunt

Abstract Background and Aims Pulmonary arterial hypertension (PAH) is a common complication of congenital heart disease (CHD). There were several variables predictor mortality in PAH-CHD from previous studies, but study with shunts has never been done, especially Indonesia. This aims to identify independent predictors among adult shunt Dr. Sardjito Hospital, Yogyakarta, Method Results We conducted retrospective cohort that included patients COHARD-PH (The Congenital HeARt Disease Hypertension) registry who recruited July 2012 - October 2020. Twelve selected as potential mortality. Predictor obtained clinical (WHO-functional class, SaO2, 6-min walking distance), laboratory (haemoglobin, NT-pro BNP), echocardiographic (pericardial effusion, defect size, TAPSE), hemodynamic (RA pressure, cardiac index, SvO2, flow ratio) data at the time diagnosis PAH. Baseline characteristics showed significantly lower systolic blood higher incidence Eisenmenger syndrome, BNP, output subjects died compared those survived. Multivariate analysis index an (OR 7.69; p = 0.011). Systolic pressure was significant confounder affecting 10.56; 0.001). Conclusion Cardiac shunts. on